Top latest Five Conolidine alkaloid for chronic pain Urban news
Most lately, it has been discovered that conolidine and the above derivatives act within the atypical chemokine receptor 3 (ACKR3. Expressed in identical parts as classical opioid receptors, it binds to the wide array of endogenous opioids. Unlike most opioid receptors, this receptor acts as a scavenger and does not activate a next messenger method